How it may work
A polyphenol studied in cellular stress-response and metabolic signalling pathways.
Guide-level evidence orientationEvidence level C
Level C describes limited, mixed or context-dependent human evidence for this exact question; read the conclusion for direction and limits.
This guide-level grade is an orientation, not a direction-of-effect label, product grade, claim or personal recommendation.Why people are interested
A plant compound associated with grapes and cellular stress-response pathways. Human results are mixed and the body absorbs it poorly.
Library trackIngredient review
Last reviewed20 Aug 2026
Guide scopeIngredient research only
What people have studied
Human trials are mixed and bioavailability is limited; broad longevity claims are unsupported.
What to consider
Potential anticoagulant and metabolic-enzyme interactions.
Local pathway
No definitive route established in first-pass screening.
Sources + indexes
See where the explanation comes from.
Open the linked research and official records behind this guide. Early topics may begin with a research index while stronger sources are added.