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Independent evidence
HomeScience LibraryEvidence methodologyResearch Radar

36 plain-language guides

Understand what
everyone is talking about.

One clear answer for every molecule: what it is, why people care and how confident the evidence is for the guide’s stated question or current orientation.

How CELLIVITY reads the research →
10Reviewed evidence packets

Defined question, outcome map and targeted source set.

26Orientation records

Useful starting context, visibly marked pending full review.

105Linked sources and indexes

Inspectable references; source count is not evidence quality.

Science lane

Reviewed records name the exact question their grade answers; other records remain guide-level orientations pending question-specific review. Outcome-specific grades can differ. None is a product grade, recommendation or proof of a CELLIVITY formula.

Performance
Reviewed evidence packetEvidence level B

Creatine

Creatine monohydrate

Helps muscles recycle energy during short, intense effort. It is one of the best-studied tools for supporting strength and training performance.

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Mitochondria
Reviewed evidence packetEvidence level C

Coenzyme Q10

CoQ10 · Ubiquinone · Ubiquinol

CoQ10 is part of mitochondrial energy-transfer biology, but that role does not guarantee more energy in daily life. Human trials raise blood CoQ10 more reliably than they improve fatigue, performance or physical function.

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Cardiometabolic
Reviewed evidence packetEvidence level C

Omega-3

EPA · DHA

EPA and DHA become part of cell membranes and influence blood fats and signalling. The result depends strongly on the dose, source and person.

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Metabolic
Orientation · full review pendingEvidence level C

Taurine

2-aminoethanesulfonic acid

A naturally occurring compound involved in fluid balance, bile acids, nerves and muscle function. Its role in healthy ageing is still being clarified.

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Cell defence
Reviewed evidence packetEvidence level C

Astaxanthin

Natural astaxanthin

Astaxanthin is a red carotenoid often sourced from algae. Small human trials show a few instrument-measured skin and exercise-marker signals, while visible rejuvenation, faster recovery and longevity remain unproven.

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Cell defence
Reviewed evidence packetEvidence level C

GlyNAC

Glycine + N-acetylcysteine

GlyNAC combines glycine and NAC, two substrates used to make glutathione. One very small longer trial was encouraging, but a larger short trial missed its main whole-blood glutathione result.

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Nutrient sensing
Orientation · full review pendingEvidence level C

Resveratrol

trans-Resveratrol

A plant compound associated with grapes and cellular stress-response pathways. Human results are mixed and the body absorbs it poorly.

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NAD+ biology
Orientation · full review pendingEvidence level C

NMN

Nicotinamide mononucleotide

A raw material the body can use to make NAD+, a molecule involved in cellular energy. It can change biomarkers, but lasting benefits remain uncertain.

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Mitochondria
Reviewed evidence packetEvidence level E

Urolithin A

UA

A gut-derived molecule studied around mitochondrial quality control. One direct formulation clearly raised measured exposure, but walking, muscle and biomarker results remain mixed or exploratory, and no human trial shows longer lifespan or validated healthspan.

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Cell defence
Reviewed evidence packetEvidence level E

Ergothioneine

L-Ergothioneine · EGT

A food-derived compound transported into cells by OCTN1. Exact preparations can raise measured blood exposure, but the largest cognition trial was primary-null and no human trial shows longer lifespan or validated healthspan.

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Metabolic
Orientation · full review pendingEvidence level D

Calcium AKG

Ca-AKG · Alpha-ketoglutarate

A form of a molecule used in the cell's energy cycle. Longevity interest is high, but strong controlled human outcome data are still limited.

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Autophagy
Reviewed evidence packetEvidence level E

Spermidine

Polyamine

A natural polyamine involved in cellular-maintenance pathways. Dietary associations are interesting, but the largest cognition trial was null and no completed supplement trial shows longer lifespan or validated healthspan.

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NAD+ biology
Orientation · full review pendingEvidence level C

Nicotinamide Riboside

NR

A vitamin B3-related ingredient that can raise NAD-related markers. Biomarker changes are clearer than meaningful real-world benefits so far.

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Mitochondria
Orientation · full review pendingEvidence level D

PQQ

Pyrroloquinoline quinone

A redox-active nutrient-like compound studied around mitochondrial signalling. Human studies are few and mostly measure indirect outcomes.

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Senescence
Orientation · full review pendingEvidence level E

Fisetin

Flavonol

A plant flavonoid studied for its possible effects on ageing cells. Most evidence is still laboratory or animal research, with human trials ongoing.

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Cell defence
Reviewed evidence packetEvidence level E

Sulforaphane

Broccoli sprout isothiocyanate

A broccoli-derived compound studied in cellular-defence signalling. Formulation and conversion strongly affect measured exposure, but exposure is not efficacy and no human trial shows longer lifespan or validated healthspan.

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Metabolic
Orientation · full review pendingEvidence level B

Berberine

Berberis alkaloid

A plant alkaloid that influences glucose and metabolic signalling. Human research exists, but interactions and product quality matter greatly.

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Medical
Orientation · full review pendingEvidence level D

Metformin

Biguanide medicine

A medicine that lowers liver glucose output and changes cellular energy signalling. Its established role is metabolic care, not general anti-ageing use.

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Medical
Orientation · full review pendingEvidence level D

Rapamycin

Sirolimus

A medicine that turns down the mTOR growth pathway. Animal longevity results are striking, but human ageing evidence and safety trade-offs remain unresolved.

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Medical
Orientation · full review pendingEvidence level D

Acarbose

Alpha-glucosidase inhibitor

Slows the digestion of carbohydrates and reduces post-meal glucose spikes. Its medical use does not automatically translate into a longevity effect.

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Medical
Orientation · full review pendingEvidence level D

Canagliflozin

SGLT2 inhibitor

Helps the kidneys remove glucose from the blood. It has important medical uses, but healthy-ageing use has not been established.

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Geroscience
Orientation · full review pendingEvidence level E

17α-Estradiol

17-alpha estradiol

A form of estradiol studied mainly in animals for sex-specific metabolic and ageing effects. Human longevity relevance is not yet known.

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Peptide research
Orientation · full review pendingEvidence level E

BPC-157

Body protection compound 157

An experimental peptide explored mainly in animal injury and tissue-repair models. Reliable controlled human outcome data are not yet available.

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Peptide research
Orientation · full review pendingEvidence level E

TB-500

Thymosin beta-4 fragment

A research peptide related to thymosin biology and tissue repair. Consumer recovery and longevity benefits have not been established in controlled human studies.

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Peptide research
Orientation · full review pendingEvidence level E

MOTS-c

Mitochondrial-derived peptide

A peptide made from mitochondrial genetic material and studied in metabolic adaptation. Human treatment evidence remains at an early stage.

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Peptide research
Orientation · full review pendingEvidence level E

Epitalon

Epithalon

A small synthetic peptide promoted around sleep, pineal and telomere theories. Modern independent human research remains limited.

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Medical
Orientation · full review pendingEvidence level B

Retatrutide

Triple incretin agonist

A triple-receptor medicine candidate being studied for metabolic disease and weight management. It remains a controlled clinical research programme.

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Muscle health
Orientation · full review pendingEvidence level A

Dietary Protein

Whey protein · Complete protein

Provides the amino acids needed to maintain and build muscle. Adequate intake works best together with progressive resistance training.

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Micronutrients
Orientation · full review pendingEvidence level A

Vitamin D

Vitamin D3 · Cholecalciferol

Supports calcium balance and bone biology. Correcting a deficiency is useful; taking more is not automatically better.

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Micronutrients
Reviewed evidence packetEvidence level C

Magnesium

Elemental magnesium

A mineral used in hundreds of reactions involving energy, nerves and muscles. Benefit is most likely when intake or status is inadequate.

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Microbiome
Orientation · full review pendingEvidence level A

Soluble Fibre

Prebiotic fibre · Fermentable fibre

Feeds selected gut microbes and can support digestion, cholesterol and post-meal metabolism. Different fibres have different effects.

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Peptide research
Orientation · full review pendingEvidence level E

CJC-1295

Growth-hormone-releasing hormone analogue

An experimental peptide designed to extend growth-hormone-releasing signals. Reliable healthy-ageing or recovery benefits have not been demonstrated.

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Peptide research
Orientation · full review pendingEvidence level E

Ipamorelin

Growth-hormone secretagogue

An experimental peptide that stimulates growth-hormone signalling through the ghrelin receptor. Long-term benefits and risks remain uncertain.

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Peptide research
Orientation · full review pendingEvidence level E

GHK-Cu

Copper peptide

A copper-binding peptide studied in skin, wound and connective-tissue biology. Topical interest does not prove a whole-body longevity effect.

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Medical
Orientation · full review pendingEvidence level B

Semaglutide

GLP-1 receptor agonist · Wegovy

A GLP-1 medicine used in selected metabolic care. Its substantial human evidence relates to specific medical outcomes, not a universal longevity effect.

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Medical research
Orientation · full review pendingEvidence level E

Dasatinib + Quercetin

D+Q senolytic protocol

A medicine-plus-flavonoid combination studied for removing certain ageing cells. Human research is small and the medical risks are significant.

Read the simple guide↗
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